ACTRN12611000640909尚未招募1 期
A phase II clinical trial of vaccination of stem cell donors with Zostavax to reduce the incidence of herpes zoster in transplant recipients – a pilot study.
适应症
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 50 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Allogeneic HSCT Recipient-donor pair
- •Donor aged 50 years and over
- •Signed informed consent by donor and recipient
- •Recipients undergoing myeloablative or non myeloablative non T cell depleted allogeneic stem cell transplants from HLA identical or 1 HLA antigen mismatched siblings.
排除标准
- •Lack of informed consent
- •Inability to recruit donor and recipient as a pair
- •Autologous transplant
- •Contraindication to Zostavax in donor
- •Donor aged <50 years
- •Recipient VZV IgG negative pre-transplantation
- •Donor VZV IgG negative
- •Pregnancy of donor at randomisation
- •Inability to follow study protocol (donor and recipient)
- •Malignancy or immunosuppression of HSC donor
- •Expected HSCT within 30 to 42 days
研究者
相似试验
招募中
2 期
Clinical trial of therapeutic vaccine against HBV carriers without anti-HBV treatmentchronic hepatitis BD019694JPRN-jRCTs061210087Hiasa Yoichi200
进行中（未招募）
不适用
Phase I/II trial of vaccine therapy in curative resected prostate cancer patients using autologous dendritic cells loaded with mRNA from primary prostate cancer tissue, hTERT and surviving.Prostatic cancer patients who have received curative surgery.EUCTR2010-018770-20-NOOslo University Hospital30
进行中（未招募）
1 期
Therapeutic vaccination: Phase I / II clinical study on patients randomized blinded to the experimental vaccine or placebo regimen. we want to evaluate the safety and the immunogenicity of a vaccine that includes a first administration of theChAdOx1.tHIVconsvX product and a second one with MVA.tHIVconsvX in HIV-1 positive adults treated early and able to control the infection for a long time.HIV InfectionCTIS2024-514581-39-00Ospedale San Raffaele S.r.l.33
招募中
2 期
Clinical trial of therapeutic vaccine against chronic hepatitis B patients under NAs treatmentchronic hepatitis BJPRN-jRCTs061210086Hiasa Yoichi140
已完成
2 期
Herpes Zoster Vaccine for Bone Marrow Transplant DonorsHerpes ZosterNCT01573182University of Sydney8