NCT00378586UnknownNot Applicable
Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Herlev Hospital
- Enrollment
- 30
- Locations
- 1
Study Overview
Brief Summary
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of different inflammatory and infectious markers.
The investigators hypothesize, therefore, that there is a significant difference in the concentrations of inflammatory and infectious markers in the rectal mucosa between patients with septic shock and healthy controls.
Study Design
- Study Type
- Observational
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Septic shock
Exclusion Criteria
- •Age < 18 years
- •No next of kin
- •Pathology of the descending or sigmoid colon or rectum
- •Pregnancy
- •1st degree relatives with inflammatory bowel disease
- •Severe coagulopathy
Investigators
Study Sites (1)
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