Lactic Acid in the Rectum and Life-Threatening Infection

Completed

• Conditions: Septic Shock

• Registration Number: NCT00197938
• Lead Sponsor: Herlev Hospital

Brief Summary

Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of oxygen. This leads to increased formation of lactic acid.

The investigators hypothesize, that the more serious the condition, the higher the concentration of lactic acid will be, thus relating to the risk of multiple organ failure or death.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2005-09-14
• Study First Submitted QC: 2005-09-14
• Study First Posted: 2005-09-20
• Study Start: 2005-11
• Study Completion: 2009-04
• Status Verified: 2009-06
• Last Update Submitted: 2009-06-05
• Last Update Posted: 2009-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

• Fluid resuscitated septic shock < 24 h.

Exclusion Criteria

• Septic shock > 24 h.
• Pathology in the rectum.
• Bleeding per rectum.
• Limitation of therapy.
• Where informed consent from relatives cannot be obtained.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (5)

Dept. of Intensive Care, Herlev University Hospital; 🇩🇰 Herlev, Denmark

Dept. of Intensive Care, Tampere University Hospital; 🇫🇮 Tampere, Finland

Dept. of Intensive Care 4131, Rigshospitalet; 🇩🇰 Copenhagen, Denmark

Dept. of Intensive Care, Glostrup University Hospital; 🇩🇰 Glostrup, Denmark

Dept. of Intensive Care, Gentofte University Hospital; 🇩🇰 Hellerup, Denmark