Progressive Resistance Exercise in Rheumatoid Arthritis Patients: a Randomized Controlled Trial

Federal University of São Paulo1 site in 1 country60 target enrollmentJuly 2011

ConditionsRheumatoid Arthritis

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Rheumatoid Arthritis
Sponsor: Federal University of São Paulo
Enrollment: 60
Locations: 1
Primary Endpoint: Change in pain - Visual analogue scale
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

A randomized controlled trial with rheumatoid arthritis patients will be realized. Patients will be randomized into two groups. Experimental group will do a 12 weeks training of progressive resistance exercise for global muscles and remain with the clinical treatment and the control only remain with the clinical treatment. Patients will be evaluated at baseline, after 6, 12 and 24 weeks.

Registry

clinicaltrials.gov

Start Date

July 2011

End Date

October 2015

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Federal University of São Paulo

Responsible Party

Principal Investigator

Felipe Martinelli Lourenzi

Federal University of São Paulo

Eligibility Criteria

Inclusion Criteria

•Rheumatoid arthritis according to American College of Rheumatology 2010
•Both genders
•Age between 18 and 65 years
•Functional class I, II and III
•Stable medication within the three months preceding the study
•Haven't done any kind of regular exercise (two or more times per Week) for at least three months before study start
•Have agreed to participate in the study and signed an informed consent form.

Exclusion Criteria

•Participating in another type of study
•Have difficulty understanding the evaluation tools with fibromyalgia
•Joint deformities that make impossible do the exercises
•Other musculoskeletal diseases
•Other diseases that contraindicate exercises.

Outcomes

Primary Outcomes

Change in pain - Visual analogue scale

Time Frame: baseline, 6, 12 and 24 weeks

Secondary Outcomes

Change in quality of life - Short form 36(baseline, after 6, 12 and 24 weeks)
Change in strength - 1 maximum repetition(baseline, after 6, 12 and 24 weeks)
Change in function capacity - Health Assessment questionaire(Baseline, after 6, 12 and 24 weeks)