Study evaluating the safety and efficacy of YAG laser for the treatment of vitreous opacity

Not Applicable

Completed

• Conditions: Treatment of symptomatic posterior vitreous detachment via YAG laser vitreolysis.; Eye Diseases

• Registration Number: ISRCTN12191616
• Lead Sponsor: Harbin Aier Eye Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-03-31
• Study Start: 2022-10-13
• Last Update Posted: 28 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 306

Inclusion Criteria

Current inclusion criteria as of 14/11/2022:

1. Symptomatic vitreous opacities owing to complete PVD (Weiss ring), symptoms for at least 3 months
2. No sensation of flashing for at least 2 weeks
3. Clear optical media
4. The distance between floaters and retina or lens was over 3mm (measured by B-scan ultrasound)
5. The 10-point visual disturbance score of at least 4
6. Ability to undertake YAG laser procedure
7. Acceptance of related risks

_____

Previous inclusion criteria:

1. Symptomatic vitreous opacities owing to complete PVD (Weiss ring), symptoms for at least 3 months
2. Clear optical media
3. The distance between floaters and retina or lens was over 3mm (measured by B-scan ultrasound)
4. The 10-point visual disturbance score at least 4
5. Ability to undertake YAG laser procedure
6. Acceptance of related risks

Exclusion Criteria

Current exclusion criteria as of 11/11/2022:

1. Snellen BCVA was worse than 20/50
2. Patients with a history of glaucoma, severe cataract, vitreous hemorrhage, retinal disease, macular disease.

_____

Previous exclusion criteria as of 18/10/2022:

1. Snellen BCVA was worse than 20/50
2. Less than 50% of the Weiss ring was ablated after one treatment (objective changes were evaluated by the surgeon who performed the YAG laser vitreolysis); patients with a history of glaucoma, severe cataract, vitreous hemorrhage, retinal disease, macular disease.

_____

Previous exclusion criteria:

1. Snellen BCVA was worse than 20/50
2. Eyes with intraocular lens (IOL)
3. Less than 50% of the Weiss ring was ablated after one treatment (objective changes were evaluated by the surgeon who performed the YAG laser vitreolysis); patients with a history of glaucoma, severe cataract, vitreous hemorrhage, retinal disease, macular disease.

Study & Design

• Study Type: Interventional
• Study Design: Not specified