Impact of Embryo Cryopreservation on Birth Weight

Completed

• Conditions: Infertility

• Registration Number: NCT03989843
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort. The aim of this study was to determine whether the freezing-thawing procedure is involved in such difference.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-05-01
• Primary Completion: 2015-06-01
• Study Completion: 2015-06-30
• Status Verified: 2019-06
• Study First Submitted: 2019-06-14
• Study First Submitted QC: 2019-06-14
• Study First Posted: 2019-06-18
• Last Update Submitted: 2019-06-19
• Last Update Posted: 2019-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 183

Inclusion Criteria

• sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015.

Exclusion Criteria

• Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
birthweight	1 day	change after FET than after fresh embryo transfer

Trial Locations

Locations (1)

Uh Montpellier; 🇫🇷 Montpellier, France