Education and activity programs to improve health in people with painful knee osteoarthritis. A randomised controlled trial with cost-effectiveness analysis

The University of South Australia0 个研究点目标入组 198 人开始时间: 2020年10月13日最近更新: 2022年1月31日

适应症

试验速览

暂无简介。

•i)Aged greater than or equal to 50 years
•ii)Average knee pain intensity of at least 4/10 (overall and/or while walking) over past week using a 0-10 numerical rating scale, where 0 = no pain at all and 10 = worst pain possible
•iii)Moderate disability due to the knee over the past week (greater than or equal to 3 on the Global Disability Rating Scale)
•iv)Painful knee OA at least 6 months duration that meets the NICE diagnostic criteria for symptomatic knee OA

•i)Conditions that prevent safe participation in physical activity as listed in the American College of Sports Medicine guidelines (e.g., cardiac or lung disease)
•ii)Pain in other body areas that currently limits walking ability (e.g., back pain, foot pain, hip pain)
•iii)Neurological disorders affecting lower limb movement (e.g., multiple sclerosis, stroke)
•iv)Inflammatory arthritis (including rheumatoid arthritis)
•v)Fibromyalgia
•vi)Previous knee replacement (on painful knee) or planned knee replacement/surgery (next 6 months) or recent knee replacement on the non- or less-painful knee (<6 months)
•vii)Previously operated knee is the most painful knee
•viii)Intra-articular therapy use in the 12 weeks preceding enrolment
•ix)Any condition impacting decision-making/memory (e.g., Alzheimer’s, dementia)
•x)Severe depression (>17 on the 4-item PROMIS depression subscale)
•xi)Current moderate/vigorous physical activity levels above guideline recommendations (>150 minutes/week; assessed using the Active Australia Physical Activity Questionnaire)
•xii)Current purposeful walking for exercise of 30 mins or more per day on 5 or more days per week.
•xiii)Unable to commit to study requirements (unable to attend study appointments or complete study outcomes)

发起方

The University of South Australia