Improving the Outcome of Very Preterm Infants Using Evidence-based Collaborative Quality Improvement: A Multi-center Prospective Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Morbidity;Newborn
- Sponsor
- Children's Hospital of Fudan University
- Locations
- 6
- Primary Endpoint
- Mortality or any major morbidity
- Status
- Withdrawn
- Last Updated
- 2 years ago
Overview
Brief Summary
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai
Detailed Description
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants using evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Infants born at \>=24+0 weeks' gestation and \<32+0 weeks' gestation;
- •Admitted to the participating NICUs within 7 days after birth during study period
Exclusion Criteria
- •Infants with major congenital anomalies;
- •Infants who transferred to non-participating hospitals within 24 hours after birth;
Outcomes
Primary Outcomes
Mortality or any major morbidity
Time Frame: During first NICU hospitalization (about 1-4 months)
It is a binary varibale (1/0). The variabel would be setted into "1",if death or with any of the following major morbidities: bronchopulmonary dysplasia, necrotizing stage II or above, retinopathy of prematurity stage III or above, intraventricular hemorrhage grade III or above or cystic periventricular leukomalacia and late-onset epsis
Secondary Outcomes
- Late-onset sepsis(During first NICU hospitalization (about 1-4 months))
- Length of NICU stay(During first NICU hospitalization (about 1-4 months))
- Necrotizing enterocolitis(During first NICU hospitalization (about 1-4 months))
- Retinopathy of prematurity(During first NICU hospitalization (about 1-4 months))
- Mortality(During the procedure (about 1-4 months))
- Severe brain injury(During first NICU hospitalization (about 1-4 months))
- Bronchopulmonary dysplasia(During first NICU hospitalization (about 1-4 months))