Improving the Outcome of Very Preterm Infants Using Evidence-based Collaborative Quality Improvement: A Multi-center Prospective Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Locations
- 6
- Primary Endpoint
- Mortality or any major morbidity
Study Overview
Brief Summary
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai
Detailed Description
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants using evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Sequential
- Primary Purpose
- Health Services Research
- Masking
- None
Eligibility Criteria
- Ages
- — to 120 Days (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Infants born at >=24+0 weeks' gestation and <32+0 weeks' gestation;
- •Admitted to the participating NICUs within 7 days after birth during study period
Exclusion Criteria
- •Infants with major congenital anomalies;
- •Infants who transferred to non-participating hospitals within 24 hours after birth;
Arms & Interventions
Intervention period
The 1.5-year period during which all six participating centers receive evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation, and collaborative learning
Intervention: Evidence-based collaborative quality improvement (Behavioral)
Baseline period
The 2-year period before the collaborative quality improvement intervention
Outcomes
Primary Outcomes
Mortality or any major morbidity
Time Frame: During first NICU hospitalization (about 1-4 months)
It is a binary varibale (1/0). The variabel would be setted into "1",if death or with any of the following major morbidities: bronchopulmonary dysplasia, necrotizing stage II or above, retinopathy of prematurity stage III or above, intraventricular hemorrhage grade III or above or cystic periventricular leukomalacia and late-onset epsis
Secondary Outcomes
- Late-onset sepsis(During first NICU hospitalization (about 1-4 months))
- Length of NICU stay(During first NICU hospitalization (about 1-4 months))
- Necrotizing enterocolitis(During first NICU hospitalization (about 1-4 months))
- Retinopathy of prematurity(During first NICU hospitalization (about 1-4 months))
- Mortality(During the procedure (about 1-4 months))
- Severe brain injury(During first NICU hospitalization (about 1-4 months))
- Bronchopulmonary dysplasia(During first NICU hospitalization (about 1-4 months))