JPRN-jRCTs071220071
Recruiting
Phase 2
Treatment protocol for adult acute lymphoblastic leukemia (-ALL/MRD2023-) - JSCT ALL/MRD2023
Koichi Akashi0 sites210 target enrollmentNovember 24, 2022
Conditionsacute lymphoblastic leukemia
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- acute lymphoblastic leukemia
- Sponsor
- Koichi Akashi
- Enrollment
- 210
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Cases diagnosed with acute lymphocytic leukemia in the WHO classification (2017\) with more than 26% blasts in the bone marrow, or mixed phenotype acute leukemia (MPAL) in the WHO classification (2017\). Patients with more than 26% blasts in the bone marrow and undergoing ALL\-directed chemotherapy. The WHO classification (2017 edition) is used as the diagnostic criteria for MPAL in this study.
- •3\.First\-time treatment patients who have not received chemotherapy or radiotherapy.
- •3\.Patients aged between 16 and 65 years old.
- •4\.Performance status (ECOG): 0 to 2 cases.
- •5\.Cases without severe organ damage. T. Bil\=\<2\.0mg/dL, Cr\=\<2\.0mg/dL
- •6\.Patients who have given written consent from the patient after explaining the content of this research. However, in the case of minors, written consent has been obtained from the legal representative and the individual.
Exclusion Criteria
- •1\. Blast cell surface immunoglobulin\-positive Burkitt leukemia.
- •2\.Patients with active double cancer.
- •3\.Patients with difficult\-to\-control infections.
- •4\. Cases with severe mental disorders.
- •5\. Pregnant cases.
- •6\.Other cases judged inappropriate by the attending physician.
Outcomes
Primary Outcomes
Not specified
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