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Treatment protocol for adult acute lymphoblastic leukemia

Phase 2
Conditions
acute lymphoblastic leukemia
Registration Number
JPRN-jRCTs071190036
Lead Sponsor
Akashi Koichi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

1. acute lymphoblastic leukemia by WHO classification
2. peroxidase positive rate of the blast cell, 3% are less than it
3. The first time treatment example which does not catch chemotherapy or the radiotherapy
4. The case that is equal to or less than 65 years old more than age 16 years old
5. Performance status 0-2
6. A case without the dangerously ill internal organs disorder
T.Bil equal to or less than 2.0mg/dL, Cr equal to or less than 2.0mg/dL
7. The case that an agreement by the document is provided from a patient on explanation because of final examination contents

Exclusion Criteria

1. B-ALL(L3) of the blast cell cell surface immune globulin positive
2. A case having double cancers
3. A case with an infectious disease having difficulty with control
4. A case with a severe mental disorder
5. The pregnancy woman
6. the case that the medical attendant judged to be inappropriate

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
3 years disease-free survival
Secondary Outcome Measures
NameTimeMethod
3 year, and 5 years overall survival<br>5 years disease-free survival<br>3 year, and 5 years CR rate<br>CR rate,MRDneg rate<br>Perfection rate of protocol regimen<br>Treatment related mortality rate<br>Treatment-related toxicities
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