Effect of Early Physical Exercise on Pulmonary Ventilation and Recruitment Evaluated With Electric Impedance Tomography.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Change in pulmonary electric impedance tomography (EIT) before, during and after single session of exercise.
研究概览
简要总结
In the critically patient bed rest and immobilization are some of the responsable of the development of respiratory complications. Early physical exercise is a tool to prevent respiratory complications as lost of respiratory muscle strength, decrease in functional residual capacity and hypoxemia improving oxygenation.
New technology as electrical impedance tomography (EIT) are available to visualize changes of regional lung aeration.
The aim of this study is to assess the effect of early physical exercise improving alveolar recruitment and pulmonary ventilation in intensive care unit (ICU) patients, evaluated with EIT.
The ICU patients included at day of evaluation will be evaluated continuously with EIT in different positions. 1) in the supine position (at 30° of inclination), 2) Sitting in chair 3) Active physical exercise 4) And rest in chair after exercise
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patient admitted at the Intensive Care Medical/Surgical Unit of Clinic Saint Luc
- •Days of hospitalization between 1 and 10
- •Hemodynamically stable
- •Patient or family member sign the informed consent
排除标准
- •With risk of evisceration
- •Therapy withdrawal
- •With cardiac devices (Pace Maker)
- •Persistent cough
- •Patches or open wounds in zone of electrodes
- •Presence of high vasopressor medication (noradrenaline > 3 mg/h)
- •PEEP > 15 cm H2
- •Acute Myocardial Infarction
- •Active bleeding
- •Intracranial pressure > 20 mm Hg or with major instability
结局指标
主要结局
Change in pulmonary electric impedance tomography (EIT) before, during and after single session of exercise.
时间窗: Meassure of EIT after 10 minutes of exercise and will be compared with baseline EIT
The change in pulmonary recruitment and ventilation will be evaluated with electric impedance tomography (EIT) in single session of exercise. First measure will be made for five minutes with EIT, before the exercise, then second measure will be made during exercise for ten minutes with EIT and finally last measure will be made after exercise for twenty minutes with EIT. All impedanciometries obtained in the patient in different activities will compare each.
次要结局
- Change in PaO2 before, during and after single session of exercise(Measure of PaO2 after 20 minutes of exercise and will compared with baseline PaO2)