Effect of Early Passive Verticalization in Pulmonary Recruitment Evaluated With Electric Impedance Tomography
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Change in pulmonary electric impedance tomography (EIT) before, during and after single session of early passive verticalization
研究概览
简要总结
In the critically patient bed rest and inmovilization are some of the responsable of the development of respiratory complications. Early physical exercise is a tool to prevent respiratory complications as lost of respiratory muscle strength, decrease in functional residual capacity and hypoxemia improving oxygenation. In some cases critically ill conditions implies use of pharmacological sedation. That condition limit the active physical exercise. However, some technicals aids as Tilt table allows execution of passive early movilization.
The aim of this study is to assess the effect of early passive verticalization assisted by tilt table on alveolar recruitment and pulmonary ventilation in intensive care unit (ICU) patients, evaluated with electrical impedance tomography (EIT) ICU patients included at day of evaluation will be evaluated consecutively with EIT in three stages; 1) in the supine position (at 30° of inclination), 2) verticalized in tilt table (at 60º of inclination) 3) in the supine position (at 30° of inclination)
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient admitted at the Intensive Care Medical/Sirurgical Unite of Clinic Saint Luc
- •Days of hospitalization between 1 and 10
- •Hemodynamically stable
- •Patient or family member sign the informed consent
- •Sedated patients
排除标准
- •With risk of evisceration
- •Therapy withdrawal
- •With cardiac devices (Pace Maker)
- •Persistent cough
- •Patches or open wounds in zone of electrodes
- •Presence of high vasopressor medication (noradrenaline > 3 mg/h)
- •PEEP > 15 cm H2
- •Acute Myocardial Infarction
- •Active bleeding
- •Intracranial pressure > 20 mm Hg or with major inestability
结局指标
主要结局
Change in pulmonary electric impedance tomography (EIT) before, during and after single session of early passive verticalization
时间窗: Meassure of EIT during 10 minutes of early passive verticalization and will compared with baseline EIT
The change in pulmonary recruitment will be evaluated with electrical impedance tomography (EIT) in single session of early passive verticalization. First measure will be made for five minutes with EIT, in bed; second measure will be made during passive verticalization for ten minutes with EIT and last measure will be made after verticalization for twenty minutes with EIT. All impedanciometries obtained in the patient in different activities will compare each.
Change in PaO2 before, during and after single session of early passive verticalization
时间窗: Meassure of PaO2 after 20 minutes of passive verticalization and will compared with baseline PaO2
Before passive verticalization will be taken a sample of arterial blood gases for determinate the initial PaO2 of the patient. Twenty minutes after passive verticalization will be taken a new sample of arterial blood gases to establish the diference between PaO2 before verticalization and after verticalization
次要结局
未报告次要终点
