''Impact of Early vs. Delayed Prone Positioning on Oxygenation and Mortality in COVID-19 ARDS Patients: A Retrospective Analysis''

Bakirkoy Dr. Sadi Konuk Research and Training Hospital1 site in 1 country350 target enrollmentOctober 3, 2022

ConditionsMorality Oxygenation Indices Hypoxia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Morality
Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Enrollment: 350
Locations: 1
Primary Endpoint: Oxygen Saturation Index (OSI)
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The goal of this study is to understand if there is any improvement on oxygenation of patients diagnosed with Covid-19 ARDS patients when we extend the duration of prone positioning.

Second outcome of the study is to investigate mortality of patients when we extend the duration of prone positioning.

Registry

clinicaltrials.gov

Start Date

October 3, 2022

End Date

February 15, 2024

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•COVİD 19 ARDS patients patients who have been intubated for 48 hours and more

Exclusion Criteria

•Pediatric patients Patients who extubated in less than 48 hours Patients with Lung and pleural malignancies

Outcomes

Primary Outcomes

Oxygen Saturation Index (OSI)

Time Frame: 48 hours

OSI is calculated by dividing the product of mean airway pressure (MAP) and FiO2 with SpO2

Oxygenation Index

Time Frame: 48 hours

Oxygenation index is calculated as OI = MAP × Fio2 × 100 / Pao2, where MAP indicates mean airway pressure and Fio2 indicates fraction of inspired oxygen