Superficial Cervical Plexus Block for Postoperative Chronic Pain

Not Applicable

Completed

• Conditions: Neurosurgery
• Interventions: Procedure: Superficial cervical plexus block; Other: Control group

• Registration Number: NCT05108337
• Lead Sponsor: Beijing Tiantan Hospital

Brief Summary

The incidence of postoperative chronic pain after craniotomy is high. Postoperative chronic pain seriously affects patient's quality of life. Compound local scalp nerve block is a good choice for analgesia after craniotomy. However, the scalp nerve block commonly cannot cover the area of suboccipital retrosigmoid approach craniotomy, leading to incomplete block. Superficial cervical plexus block (SCPB) is theoretically promising to solve the analgesia requirements of such surgical approach. At the same time, ultrasound guidance can not only accurately locate, ensure the effect of block and avoid accidental injury during puncture. The purpose of this study is to explore whether ultrasound-guided superficial cervical plexus block can safely and effectively reduce the incidence of chronic pain after craniotomy via suboccipital retrosigmoid approach.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-21
• Study First Submitted QC: 2021-11-03
• Study Start: 2021-11-04
• Study First Posted: 2021-11-04
• Primary Completion: 2023-11-22
• Study Completion: 2023-11-22
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-20
• Last Update Posted: 2024-01-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 292

Inclusion Criteria

1. Elective suboccipital retrosigmoid approach approach craniotomy;
2. Age between 18 and 65 years;
3. American Society of Anesthesiologists (ASA) physical status I-III.

Exclusion Criteria

1. The patients or legal clients refuse to provide informed consent;
2. Local infection;
3. Preoperative impairment of consciousness and cognitive function;
4. Uncontrolled hypertension;
5. Inability to communicate;
6. Allergies to experimental drugs;
7. History of drug abuse;
8. History of chronic headache;
9. Aphasia and hearing impairment;
10. Patients undergoing second craniotomy;
11. Body mass index < 18.5 kg/m2 or > 35.0 kg/m2;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Scpb group	Superficial cervical plexus block	Superficial cervical plexus block group
Control group	Control group	Saline group

Primary Outcome Measures

Name	Time	Method
Chronic pain assessment	at 3 months after surgery.	Follow-up visit will be conducted by telephone at 3 months after surgery.

Trial Locations

Locations (2)

Beijing Tian Tan Hospital, Capital Medical University; 🇨🇳 Beijing, Beijing, China

Beijing Tiantan Hospital; 🇨🇳 Beijing, Beijing, China