Superficial Cervical Plexus Block for Postoperative Analgesia

Not Applicable

Completed

• Conditions: Plexus Block;Analgesia;Neurosurgery
• Interventions: Procedure: Superficial cervical plexus block; Other: Control group

• Registration Number: NCT04036812
• Lead Sponsor: Beijing Tiantan Hospital

Brief Summary

The incidence of postoperative pain after craniotomy is high. Severe postoperative pain can lead to a series of complications that are detrimental to the recovery of craniotomy patients. Compound local scalp nerve block is a good choice for analgesia after craniotomy. However, the scalp nerve block commonly cannot cover the area of suboccipital retrosigmoid approach craniotomy, leading to incomplete block. Superficial cervical plexus block (SCPB) is theoretically promising to solve the analgesia requirements of such surgical approach. At the same time, ultrasound guidance can not only accurately locate, ensure the effect of block and avoid accidental injury during puncture. The purpose of this study is to explore whether ultrasound-guided superficial cervical plexus block can safely and effectively reduce the requirement of analgesic drugs and pain after craniotomy via suboccipital retrosigmoid approach.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-07-26
• Study First Submitted QC: 2019-07-26
• Study First Posted: 2019-07-30
• Study Start: 2019-11-18
• Primary Completion: 2021-04-09
• Study Completion: 2021-04-10
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-12
• Last Update Posted: 2025-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 106

Inclusion Criteria

1. Elective suboccipital retrosigmoid approach approach craniotomy;
2. Age between 18 and 65 years;
3. American Society of Anesthesiologists (ASA) physical status I-III.

Exclusion Criteria

1. The patients or legal clients refuse to provide informed consent;
2. Local infection;
3. Preoperative impairment of consciousness and cognitive function;
4. Uncontrolled hypertension;
5. Inability to communicate;
6. Allergies to experimental drugs;
7. History of drug abuse;
8. History of chronic headache;
9. Aphasia and hearing impairment;
10. Patients undergoing second craniotomy;
11. Body mass index < 18.5 kg/m2 or > 35.0 kg/m2;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Superficial cervical plexus block group	Superficial cervical plexus block	-
Control group	Control group	-

Primary Outcome Measures

Name	Time	Method
the cumulative consumption of sufentanil by the PCA	24 hours after surgery	the cumulative consumption of sufentanil by the PCA 24 hours after surgery

Secondary Outcome Measures

Name	Time	Method
Use of analgesics by the PCA after operation	at 1, 2, 4, 48 hours after surgery.	the cumulative consumption of sufentanil by PCA
Pain severity score	at 1, 2, 4, 24, 48 hours after surgery	It will be accessed using NRS
Patient analgesic satisfaction	at 24 hours after surgery	Patient satisfaction with overall pain management will be evaluated at 24 hours after surgery using NRS
Anesthesia recovery quality score：	at 1 hour after surgery	It will be accessed at postoperative 1 and 2 hours using the Anesthesia Steward Emergence Scale. The Anesthesia Steward Emergence Scale(0-6) is divided into three parts: the degree of wakefulness - 2 points for complete recovery, 1 point for response to stimulation, 0 point for no response to stimulation; the degree of airway patency - 2 points for cough according to the doctor's order, 1 point for maintenance of airway patency without support, 0 point for support required for respiratory tract; 2 points for conscious activities of limbs with limb mobility, 1 point for unconscious activities of limbs, point for no activities of limbs.

Trial Locations

Locations (2)

Beijing Tiantan Hospital; 🇨🇳 Beijing, Beijing, China

Beijing TianTan Hospital; 🇨🇳 Beijing, China