Dynamic and Isometric Strength Analyses of Lower Extremity Blood Flow Restriction Training: A Randomized Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Cedars-Sinai Medical Center
- Enrollment
- 16
- Locations
- 2
- Primary Endpoint
- the changes in Force plate measures from baseline to 16 weeks
Study Overview
Brief Summary
The purpose of this research is to determine the effects of low-load blood flow restriction (BFR) training compared to conventional strengthening using dynamic force plate and isometric force frame analyses in healthy subjects.
Detailed Description
The purpose of this research is to determine the effects of low-load blood flow restriction (BFR) training compared to conventional strengthening using dynamic force plate and isometric force frame analyses in healthy subjects. The primary research procedures are:
Subjects will be randomized into either BFR or conventional strengthening groups.
BFR and conventional strengthening programs will be implemented. Force plate and force frame data will be collected at baseline, 4, 6, 8, 12, and 16 weeks.
Subject Population. The study will enroll 18 healthy volunteers. The study includes 6 visits.
The total study duration for each subject is 16 weeks.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy volunteers without history of knee pathology requiring physical therapy or surgery
- •Individuals between 18 and 40 years old
Exclusion Criteria
- •History of venous thromboembolism or other hematologic disorder Pregnant
- •Coronary artery disease, peripheral arterial disease, or hypertension (> 140/90 mmHg)
Outcomes
Primary Outcomes
the changes in Force plate measures from baseline to 16 weeks
Time Frame: Measured at 4,6,8,12 and 16 weeks.
Relative strength index (RSI)
the change in Force plate measures from baseline to 16 weeks
Time Frame: Measured at 4,6,8,12 and 16 weeks.
Displacement
the changes in Force Frame measure from baseline to 16 weeks
Time Frame: Measured at 4,6,8,12 and 16 weeks.
Velocity M/sec
The change in Force plate measures from baseline to 16 weeks
Time Frame: Measured at 4,6,8,12 and 16 weeks.
Power (W)
the changes in Force Frame measures from baseline to 16 weeks
Time Frame: Measured at 4,6,8,12 and 16 weeks.
Force (N)
Secondary Outcomes
No secondary outcomes reported
Investigators
Orr Limpisvasti
Principal Investigator
Cedars-Sinai Medical Center