The Duration of Effects of Massage in Healthy Participants

Not Applicable

Completed

• Conditions: Pressure Pain Threshold; Massage; Healthy

• Registration Number: NCT05317702
• Lead Sponsor: University of Central Florida

Brief Summary

Massage is a common rehabilitation treatment for musculoskeletal pain. Prior studies indicate massage applied with a deep pressure that induces a moderate amount of pain produces a lessening of pain sensitivity compared to light touch, pain free massage. The investigators now aim to investigate how long pain sensitivity changes last after 4 minutes of moderately painful massage and determine factors that help predict who displays a lessening of pain sensitivity.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-21
• Study First Submitted QC: 2022-03-30
• Study First Posted: 2022-04-08
• Study Start: 2022-06-21
• Status Verified: 2022-07
• Primary Completion: 2022-07-12
• Study Completion: 2022-07-12
• Last Update Submitted: 2022-07-12
• Last Update Posted: 2022-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• pain-free

Exclusion Criteria

• Non-English speaking
• Systemic medical condition known to affect sensation (i.e. uncontrolled diabetes)
• Regular use of prescription pain medication
• Current or history of chronic pain condition
• Currently taking a blood-thinning medication
• Any blood clotting disorder, such as hemophilia
• Contraindications to the application of a blood pressure cuff to the arm, such as: lymphedema or arterial/venous lines
• Contraindications to elevating the arm above the head or exercising the arm with a light weight, such as a recent surgery or fracture
• Investigator is unable to locate myofascial trigger point in the upper trapezius during testing session

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change in Pressure Pain Threshold	PPT is applied between minutes 1, 2, 3, and 4 of massage. PPT is also applied at minutes 1,3,5,10,15 after massage. A higher PPT indicates a lessening of pain sensitivity.	A digital pressure algometer will be applied to the web space of the foot opposite the trigger point. Participants are instructed to say "stop" or "pain" so the stimulus can be terminated "when the sensation first transitions from pressure to pain" (pain threshold). Participants will rate the pain experienced during the threshold testing using a 101-point numeric pain rate scale (NPRS) anchored with 0= no pain to 100= the most intense pain sensation imaginable immediately following each testing time.

Secondary Outcome Measures

Name	Time	Method
Temporal Summation	Applied before massage	Mechanical temporal summation will be examined using a neuropen with neurotip. The neuropen with a neurotip has a semi-sharp point that exerts 40g of pressure. A series of ten pinpricks applied to the palmar surface of the hand opposite the trigger point identified at the beginning of the study visit (if the trigger point is on the left shoulder, the right palm will be used for this test.). Participants will rate the pain intensity of each pinprick using a numerical pain rating scale from 0-100 where 0=no pain and 100=worst pain imaginable. A higher pain rating indicates more pain.
Conditioned Pain Modulation	Applied before massage	First, PPT will be measured on the foot opposite the trigger point. Second, the arm on the same of the participant's trigger point will be elevated for one minute. A blood pressure cuff will be inflated to 270 mmHg and the participant will return his or her arm to the horizontal position. The participant will repeatedly extend the wrist 20 times with a light weight. Third, PPT will be repeated on the top of the foot.

Trial Locations

Locations (1)

University of Central Florida; 🇺🇸 Orlando, Florida, United States