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Adverse Drug Reactions in Pediatrics: Experience of a Regional Pharmacovigilance Center

Completed
Conditions
Child With Adverse Drug Reactions
Interventions
Other: Adverse drug reaction
Registration Number
NCT03316014
Lead Sponsor
CHU de Reims
Brief Summary

Aim. - To describe the adverse drug reactions (ADR) and the drugs involved in pediatrics.

Methods. - An observational study on all ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014 involving children from 0 to 17 years inclusive was performed. For all notifications, we studied the patient and the ADR characteristics

Detailed Description

Pediatry aged under 18 years accounted for around 22% of the French general population.

Data regarding drug safety from clinical trials are insufficient in this population.

Aim. - To describe the adverse drug reactions (ADR) and the drugs involved in pediatrics.

Methods. - An observational study on all ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014 involving children from 0 to 17 years inclusive was performed. For all notifications, we studied the patient and the ADR characteristics.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
632
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Adverse drug reactionAdverse drug reactionChildren from 0 to 17 years inclusive with ADR notifications recorded in the French pharmaco-vigilance database by the Regional Pharmacovigilance Center of Champagne-Ardenne between 1 January 1985 and 31 December 2014
Primary Outcome Measures
NameTimeMethod
the different type of ADR30 years
Secondary Outcome Measures
NameTimeMethod
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