Effect of vitamin supplementation on pulmonary fibrosis patients

Phase 3

• Conditions: pulmonary fibrosis.; Other interstitial pulmonary diseases with fibrosis

• Registration Number: IRCT201612202365N15
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Adults (20 years<) with idiopathic pulmonary fibrosis and according to the guidelines of Thoracic Society United States of America and Respiratory Health Association of Europe and final confirmation of respiratory disease physician, patients diagnosed for more than 6 months; Both sex; Avoiding the use of vitamin supplements Exclusion criteria: Unwillingness of individuals to continue participating in the study; Admission supplement inadequate (less than 80% of supplements)

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percent of Forced Exspiratory Volume in First Second FEV1. Timepoint: before intervention and 3 month after starting the intervention. Method of measurement: spirometry.

Secondary Outcome Measures

Name	Time	Method
Transforming growth factor ß1. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Inspiratory Reserve volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Expiratory Reserve Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Protein carbonyls. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Residual Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Tidal Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;High-sensitivity c-reactive protein. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Erythrocyte sedimentation rate. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.