Effect of Vitamin C and Vitamin E Supplementation on Postprandial Oxidative Stress, Inflammatory Markers, Lipid Profile , Insulin and Blood Glucose Level of Type 2 Diabetic Patients
Phase 2
- Conditions
- diabetes mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT138904073236N1
- Lead Sponsor
- Shiraz Uuniversity Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1- having diabetes
2- normal blood pressur
3- age between 25 to 65
4- having diabetes for maximum 15 years
5- nonsmoker, nonalcoholic
6- not taking vitamin and/or mineral supplement, insulin therapy, lipid lowering, hormone replacement therapy, diuretics or ß-blockers and aspirin
7- no history or clinical evidence of overt vascular disease, acute or chronic inflammatory disease and kidney stones
8- no history of radiation therapy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood glucose fasting and postprandial. Timepoint: 4 times, before and 6 weeks after intervention, fasting and postprandial. Method of measurement: Auto analyser.;Insulin Fasting and postprandial. Timepoint: 4 times,before and after intervation, fasting and postprandial. Method of measurement: Radio Immune Assay.
- Secondary Outcome Measures
Name Time Method ipid profile. Timepoint: before and 6 weeks after intervention, fasting and postprandial. Method of measurement: auto analyser.;Malondialdehyde. Timepoint: before and 6 weeks after intervention. Method of measurement: spectrophotometery.;High sensetive C-Reactive Protein. Timepoint: before and 6 weeks after intervention, fasting and postprandial. Method of measurement: ELIZA.;Interlukin-6. Timepoint: before and 6 weeks after intervention, fasting and postprandial. Method of measurement: Radio Immune Assay.