The effect of vitamin E and C on risk factors of coronary artery disease (CAD)

Phase 3

Conditions: Coronary artery disease (CAD).
Atherosclerotic heart disease of native coronary artery

Registration Number: IRCT20180804040688N1

Lead Sponsor: Gonabad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 88

Inclusion Criteria

Inclination to participate in research
Certification of physician to receive vitamins E and C
Age 18 to 50 years old
Acceptable listening, speaking and consciousness to answer the questions
Waist circumference is more than 102 cm in men and more than 88 cm in women
Fasting triglyceride equal to or greater than 150 mg/dl
HDL less than 40 mg/dl
Systolic blood pressure equal to or greater than 135 mm Hg
Fasting glucose is greater than or equal to 110 mg/dl

Exclusion Criteria

Not pregnant
Do Not taking corticosteroids and contraceptives
Lack of underlying diseases (such as kidney and liver failure, thyroid dysfunction, malignancy, mental, autoimmune and infectious diseases)
Lack of specific medical conditions requires as a change in diet and exercise program
Lack of insulin treatment
The need for surgery during the study
Cancellation request of the patient
Incidence of unwanted side effects
Irregular consumption of supplements

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic and diastolic blood pressure. Timepoint: Before and after the intervention. Method of measurement: Mercury sphygmomanometer.;Lipid profiles. Timepoint: Before and after the intervention. Method of measurement: Laboratory instruments.;Fasting blood sugar. Timepoint: Before and after the intervention. Method of measurement: Laboratory instruments.;Body mass index (BMI). Timepoint: Before and after the intervention. Method of measurement: Weight (kilograms) / square height (meter).;C-reactive protein (CRP). Timepoint: Before and after the intervention. Method of measurement: Laboratory instruments.

Secondary Outcome Measures