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Intravesical hyaluronic acid (HA) and chondroitin sulphate (CS) for treatment of signs and symptoms of patients with late radiation tissue cystitis (LRTC): an investigative pilot study

Not Applicable
Completed
Conditions
ate radiation tissue cystitis with or without haematuria
Urological and Genital Diseases
Irradiation cystitis
Registration Number
ISRCTN37534393
Lead Sponsor
Institut Biochimique SA (IBSA) (Italy)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
30
Inclusion Criteria

Eligible patients with symptomatic LRTC after receiving primary or adjuvant radiotherapy for pelvic neoplasms

Exclusion Criteria

1. Patients (male and female, age range: 40-80 years) undergoing chemotherapy
2. Those with a life expectancy of less than 24 months
3. Those with radiological confirmed metastasis
4. Patients receiving radiotherapy for bladder cancer
5. Patients with documented urethral strictures

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The tolerability, safety and efficacy of the treatment at reducing the symptoms and signs of LRTC at 3 and 12 months
Secondary Outcome Measures
NameTimeMethod
Quality of Life (QoL), measured at 3 and 12 months
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