NCT02093416已完成不适用
Leptin Receptors in the Bariatric Surgical Population Within the University of Pittsburgh Medical System: A Cohort Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- PCR test for Leptin Receptors
研究概览
简要总结
Prospective cohort study evaluating the role of leptin receptors in the bariatric surgical population compared with non obese controls. Additionally serum levels of leptin, ghrelin, motilin and PYY will be compared amongst the different BMI classes and a quality of life questionnaire completed by all participants.
The hypothesis is that obese individuals have lower leptin receptors in enterocytes which is partially responsible for the higher serum leptin levels without appropriate control of satiety.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Endoscopic Intervention
排除标准
- •18 years of age or older
- •No acute GI bleeding
结局指标
主要结局
PCR test for Leptin Receptors
时间窗: 1 week
Endoscopic biopsies of enterocytes will be measured via PCR
次要结局
- ELISA test for ghrelin, motilin, leptin and PYY(1 week)
- IWQOL lite questionnaire(1 week)
研究者
研究点 (1)
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