Utility of Point-of-care Device for Rapid Determination of Cogulopathy in Trauma Patients
Completed
- Conditions
- Severe Trauma
- Registration Number
- NCT02869737
- Lead Sponsor
- University Hospital, Grenoble
- Brief Summary
Traumatic coagulopathy is frequent and is an independent risk factor of mortality. Its detection mainly relies upon classic biological test like the prothrombin time and the international normaliezd ratio (INR). These tests are not available at the bedside. Point of care (POC) device for INR measurement are now available like the Coaguchek, Roche, France. The aim of the present study is to test the correlation between the POC INR and the laboratory INR.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Age > 15 y-o
- Admission for severe trauma
Exclusion Criteria
- Patients under oral anticoagulant
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concordance between POC INR and laboratory INR using 3 classes: normal < 1.1, moderate : 1.1-1.5, severe: >1.5 Admission
- Secondary Outcome Measures
Name Time Method Organ failure measured with the SOFA score at Day 1 Day 1 Injury severity (ISS) Day 1 Prediction of RBC transfusion 24 hours post admission Prediction of FFP transfusion 24 hours post admission In-hospital mortality assessed using patients' files up to Day 28