Comparing the efficacy of intravenous Dexamethasone and Inhaler N-Acetyl Cysteine plus intravenous Dexamethasone in treatment of Respiratory Distress Syndrome
Phase 3
- Conditions
- Respiratory distress syndrome of newborn.Respiratory distress syndrome of newborn
- Registration Number
- IRCT2016101917413N21
- Lead Sponsor
- Vice chancellor for research, Pharmaceutical Sciences Branch, Islamic Azad University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
birth weight between 1000-2500 gr;Gestational age of less than 36 weeks;Mechanical ventilation for at least two days;Oxygen saturation of more than 30% after extubation;PH<7.2;PCO2>55;PaO2<50
Exclusion Criteria
Hemorrhagic lesions;Congenital Anomalies;Chromosomal Anomalies;early sepsis;death before 72 hours of age
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Respiratory rate. Timepoint: before and after extubation. Method of measurement: one minute counting by nurse.;PH. Timepoint: before and after extubation. Method of measurement: Arterial Blood Gas Assessment.;Blood Pressure. Timepoint: before and after extubation. Method of measurement: Monitring System.;Oxygen Saturation. Timepoint: before and after extubation. Method of measurement: Pulse Oxymetry.
- Secondary Outcome Measures
Name Time Method