Evaluation of Adverse early Outcomes of Prolonged Initial Empirical Antibiotic Therapy in Premature Infants

Not Applicable

Conditions: Very Low Birth Weight infants.
Other low birth weight

Registration Number: IRCT201210124113N3

Lead Sponsor: Pediatric Health Research center of Tabriz University of Medical Sceinces

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 150

Inclusion Criteria

Inborn preterm infants in Alzahra Teaching hospital of Tabriz
Without congenital Anomaleis
Very Low Birth weight ( VLBW): Birth Weight 1499 and less
Admit in 72 hours of life for respiratory Distress or R/O Sepsis

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
osocomial Infection. Timepoint: from 72 hours of life until Discharge. Method of measurement: Positive blood culture with clinical symptoms.;Mortality. Timepoint: From admision time until discharge or death time. Method of measurement: Evaluation ang registration form of hospital.;Necrotizing Entrocolitis ( stage 2 or more). Timepoint: after the day 5 until discharge. Method of measurement: gastrointestinal symptoms and radiologic evidence.

Secondary Outcome Measures

Name	Time	Method
Duration of hospitalization. Timepoint: from the admition time until discharge. Method of measurement: Registration Form( Medical records of the patient ).;Total days of Antibiotic therapy. Timepoint: From the first day of admission until discharge. Method of measurement: Registration form ( Medical records of the patient as days ).;Chronic Lung Disease. Timepoint: Need of Oxygen or Respiratory support more than 28 days after birth. Method of measurement: Registration form(Medical records of the patient).;Intraventricular Hemorrage ( Grade 2 or more ). Timepoint: 7-10 days after birth. Method of measurement: Brain Sonography.