NCT02188602撤回不适用
Retrospective Investigation of Chloride Dosing and Its Effect on Acute Kidney Injury
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Acute Kidney Injury
研究概览
简要总结
The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients. The investigators hypothesis is that administering intravenous fluids with higher chloride content are more likely to lead to acute kidney injury.
详细描述
Retrospective chart review from 2008-2012 evaluating chloride dosing and serum chloride levels and their effects on acute kidney injury in the pediatric ICU. Patients will be included for the first seven days of their PICU stay.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Month 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age less than 18 years
- •PICU admitting diagnosis of sepsis, respiratory failure, or hepatic failure.
排除标准
- •hyponatremia or hypernatremia at PICU admission
- •preexisting diagnosis of End-stage renal disease or renal transplant
- •presence of neurologic comorbidities.
结局指标
主要结局
Acute Kidney Injury
时间窗: 7 days
or sooner if death or discharged
次要结局
- Hospital length of stay(7 days)
- PICU length of stay(7 days)
- Mortality(7 days)
- Number of ventilator days(7 days)
研究者
研究点 (1)
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