Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty

Not Applicable

Completed

• Conditions: Rheumatoid Arthritis; Osteoarthritis

• Registration Number: NCT00493142
• Lead Sponsor: University of Alberta

Brief Summary

The purpose of this study is to determine whether a pre-operative home rehabilitation exercise program designed for knee replacements is more effective than pre-operative usual care.

Detailed Description

Patients with lower levels of function prior to total knee arthroplasty (TKA) attain lower functional endpoints after surgery. Therapeutic exercise improves function in patients with arthritis of the knee, yet little evidence has examined the impact of pre-operative exercise for TKA.

Single blinded randomized clinical trial comparing a pre-operative home exercise program to pre-operative usual care for patients who are waiting for TKA.Comparison group is usual care within the health region which does not include pre-operative rehabilitation program.

Primary outcome: WOMAC function subscale. Secondary outcomes: 1) quality of life; 2) ambulation; 3) self-efficacy; 4) anxiety; 5) patient satisfaction; 6) cost-effectiveness of this intervention.

Total Enrollment: 230 patients

If the intervention improves function prior to surgery, results will be clinically applicable for patients waiting for surgery

Study Timeline

• Study First Submitted: 2007-06-26
• Study First Submitted QC: 2007-06-26
• Study First Posted: 2007-06-28
• Study Start: 2008-07
• Primary Completion: 2013-07
• Study Completion: 2021-11-25
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-13
• Last Update Posted: 2022-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

• primary unilateral total knee arthroplasty
• poor functional status (WOMAC=50 or greater)
• 50 yrs or older
• reside within health region
• understands English

Exclusion Criteria

• unicompartmental total knee arthroplasty
• revision surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Self-reported function	5 evaluations within 6 months after surgery	Self-reported function

Secondary Outcome Measures

Name	Time	Method
Quality of life, self-efficacy, ambulation, anxiety and patient satisfaction	5 evaluations within 6 months after surgery	Quality of life
self-efficacy	5 evaluations within 6 months after surgery	self-efficacy
ambulation, anxiety and patient satisfaction	5 evaluations within 6 months after surgery	ambulation
patient satisfaction	5 evaluations within 6 months after surgery	patient satisfaction
anxiety	5 evaluations within 6 months after surgery	anxiety

Trial Locations

Locations (1)

University of Alberta- Capital Health; 🇨🇦 Edmonton, Alberta, Canada