To understand whether prediction of preeclampsia can be improved by adding study of maternal heart parameters
Not Applicable
- Conditions
- Health Condition 1: O14- Pre-eclampsia
- Registration Number
- CTRI/2024/03/064329
- Lead Sponsor
- AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Pregnant women admitted with diagnosis of PE at gestational age lesser than or equal to 34 weeks according to ISSHP criteria
2. Willing to be part pf study
Exclusion Criteria
1. Presence of fetal chromosomal or structural abnormality
2. Maternal cardiac disease
3. Hematological disorders
4. Multifetal gestation
5. Pre existing chronic hyertension
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maternal core outcomes <br/ ><br>A) Clinical parameters <br/ ><br>1. Maternal mortality <br/ ><br>2. Eclampsia <br/ ><br>3. Stroke <br/ ><br>4. Cortical blindness <br/ ><br>5. Retinal detachment <br/ ><br>6. Pulmonary edema <br/ ><br>7. Acute kidney injury <br/ ><br>8. Liver capsule hematoma or rupture <br/ ><br>9. Placental abruption <br/ ><br>10. Post partum haemorrhage <br/ ><br>11. Admission to Intensive care unit requiring intubation or mechanical ventilation (not for childbirth) <br/ ><br> <br/ ><br>Perinatal outcomes <br/ ><br>1. Stillbirth <br/ ><br>2. Gestational age at delivery <br/ ><br>3. Birthweight <br/ ><br>4. Small for gestational age <br/ ><br>5. Neonatal mortality <br/ ><br>6. Neonatal seizures <br/ ><br>7. Admission to Neonatal unit required <br/ ><br>8. Respiratory support required <br/ ><br>Timepoint: Following initial assessment patient will be followed up and managed according to institutional protocol till 7 days postpartum <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. Predictive ability of FullPIERS model for adverse maternal and perinatal outcomes in women with Pre eclampsia <br/ ><br>2. Predictive ability of sFLT/PlGF ratio with or without uterine artery doppler for adverse maternal and perinatal outcomes in women with Pre eclampsia <br/ ><br>3. Development of a multiparametric model integrating clinical, biochemical, placental and maternal cardiovascular markers for predicting adverse outcomes in women with Pre eclampsiaTimepoint: Following initial assessment, patient will be followed up and managed according to institution protocol till 7 days postpartum