Maternal cardiovascular indices in early pregnancy

Not Applicable

• Conditions: Healthy early pregnancy; Reproductive Health and Childbirth - Normal pregnancy; Spontaneous miscarriages in early pregnancy; Reproductive Health and Childbirth - Fetal medicine and complications of pregnancy

• Registration Number: ACTRN12614000241639
• Lead Sponsor: Dr Wendy H.L. Teoh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-03-06
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Twenty ASA I- II patients scheduled for elective pregnancy terminations between 8-11 gestational weeks, and 20 women with spontaneous miscarriages of <12 weeks' gestation who are scheduled for surgical uterine evacuation.

Exclusion Criteria

ASA physical status III- IV, BMI > 40 kg/m2, aged <21 or > 50years, and those with significant pre-existing cardiovascular disease pre-pregnancy eg hypertension, ischaemic heart disease, valvular heart disease, cardiomyopathy.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome of interest is systemic vascular resistance (SVR), which is measured non-invasively with the USCOM monitor.[This will be measured non-invasively with the USCOM monitor in the operating theatres, prior to the patient presenting for elective termination of pregnancies or their surgical uterine currettage (in those with spontaneous miscarriages scheduled for evacuation of uterus).]

Secondary Outcome Measures

Name	Time	Method
nil[nil]