NCT00829075已完成4 期
A Prospective, Randomized, Controlled Trial Comparing Three Different Gonadotrophin Regimens in Oocyte Donors: Ovarian Response and IVF Outcome
Instituto Valenciano de Infertilidad, IVI VALENCIA1 个研究点 分布在 1 个国家开始时间: 2005年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 试验地点
- 1
- 主要终点
- The aim of this study was to verify whether different gonadotrophin regimes could affect controlled ovarian stimulation (COS) parameters and IVF outcome in an egg donation program.
研究概览
简要总结
Exploratory study assessing the effect of three gonadotrophin protocols on Controlled Ovarian Stimulation (COS) parameters and IVF outcome in oocyte donors undergoing GnRH analogue (long protocol). 1,028 donors were randomized in three groups: Group I (n= 346) only r-FSH, Group II (n= 333) only HP-hMG and Group III (n= 349) r-FSH plus HP-hMG. IVF outcome of 1,059 oocyte recipients was compared.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 34 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •healthy women 18-34 years of age
- •regular menstrual cycles
- •no family history of hereditary or chromosomal diseases
- •normal karyotype
- •BMI 18-29 Kg/m2
- •negative screening for sexually transmitted diseases
排除标准
- •women with PCOS were not included in this study
研究组 & 干预措施
I
Experimental
only r-FSH TREATMENT
干预措施: r-FSH (Drug)
II
Experimental
only HP-hMG TREATMENT
干预措施: HP-hMG (Drug)
III
Experimental
r-FSH plus HP-hMG TREATMENT
干预措施: r-FSH plus HP-hMG (Drug)
结局指标
主要结局
The aim of this study was to verify whether different gonadotrophin regimes could affect controlled ovarian stimulation (COS) parameters and IVF outcome in an egg donation program.
时间窗: one year
次要结局
未报告次要终点
研究者
研究点 (1)
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