NCT01331733已完成不适用
Comparative Assessment of the Clinical Utility of Ovarian Stimulation With Menotropin Versus Menotropin Plus GnRH Antagonist Following Two Protocols of Ovulation Induction for Intrauterine Insemination
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 131
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
To assess the effectiveness of protocols of ovarian hyperstimulation combining urinary gonadotrophins + GnRH antagonist vs urinary gonadotrophins, to achieve clinical pregnancy in females undergoing intrauterine insemination.
Study hypothesis: protocols combining urinary gonadotrophins + GnRH antagonist should be more effective than monotherapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 36 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women aged 18-36 years
- •Body mass index (BMI) between 18 and 26
- •Prolactin within the laboratory normal range
- •Couples affected by sterility able to treat by IUI (intrauterine insemination)
- •Patients undergoing Menopur® treatment
- •Normal thyroid function
- •Regular menses (21-35 days)
- •Couples willing to participate in the study that have signed the informed consent form
- •Seminal sample REM>3 million
排除标准
- •Two previous ART (assisted reproductive technology) cycles without ongoing pregnancy
- •Policystic ovarian syndrome
- •Evidence of significant bacterial infection in the seminogram of the couple in the preceding 6 months
研究组 & 干预措施
hMG-HP
Patients with a condition
干预措施: hMG-HP (Drug)
hMG-HP + GnRH antagonist
Patients with a condition
干预措施: hMG + GnRH antagonist (Drug)
结局指标
主要结局
Clinical pregnancy rate
时间窗: 30 days
次要结局
- Live birth rate(40 weeks)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Assessment of the Therapeutic Utility of hMG-HPSterilityNCT01330784Ferring Pharmaceuticals61
已完成
不适用
Assessment of the Therapeutic Utility of r-FSH in Association With hMG-HPSterilityNCT01330771Ferring Pharmaceuticals51
已完成
4 期
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH AgonistOvarian StimulationNCT00830492Yazd Research & Clinical Center for Infertility200
已完成
4 期
Impact of Three Different Gonadotrophin Regimes on Egg Donation ProgramOvarian StimulationNCT00829075Instituto Valenciano de Infertilidad, IVI VALENCIA
已完成
不适用
Assessment of the Effectiveness and Tolerability of Ovarian HyperstimulationSTERILITYNCT01331720Ferring Pharmaceuticals279