NCT01330771已完成不适用
Assessment of the Therapeutic Utility of r-FSH in Association With hMG-HP Within a Protocol of Controlled Ovarian Hyperstimulation in IVF in Normoresponders Women Undergoing Downregulation With GnRH Antagonist
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
To assess the effectiveness of a protocol of ovarian hyperstimulation combining urinary gonadotrophins + recombinant gonadotrophins, to achieve clinical pregnancy in females undergoing IVF.
Study hypothesis: to assess the effectiveness of protocols combining urinary gonadotrophins + recombinant gonadotrophins
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 38 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women aged 18-38 years
- •Body mass index (BMI) between 18 and 30
- •Women classified as normogonadotrophin patients. Not more than 3 previous cycles of ART (assisted reproductive technology)
- •Testosterona, FSH (follicle-stimulating hormone), LH (luteinizing hormone) and Prolactin serum levels during the early folicular phase (days 2-4 of the cycle) within the laboratory normal range
- •No administration of clomiphen citrate or gonadotropins during the month prior to the start of the study
排除标准
- •Failure in previous cycles of assisted reproduction IVF/ICSI (in-vitro fertilisation/intracytoplasmic sperm injection)
- •Seminal samples not apt for IVF-ICSI (according to the criteria of each center). Evidence of significant bacterial infection in the seminogram of the couple in the preceding 6 months
- •Data suggestive of possible ovarian failure
- •Antecedents of severe ovarian hyperstimulation syndrome (OHSS)
- •Important systemic disease
- •Pregnancy or contraindication to pregnancy
研究组 & 干预措施
hMG-HP/r-FSH
Patients with a condition
干预措施: hMG-HP/r-FSH (Drug)
结局指标
主要结局
Clinical pregnancy rate
时间窗: 30 days
次要结局
- Biochemical pregnancy rate(16 days)
研究者
研究点 (1)
Loading locations...
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