Study of a Vestibular Biomarker of Phase in Bipolar Disorder

• Conditions: Depression, Bipolar; Bipolar Disorder
• Interventions: Device: Vestibular test

• Registration Number: NCT02827045
• Lead Sponsor: Vest Brain,Centro de Estudios Neurovestibulares

Brief Summary

Bipolar Disorder show cyclic changes of mood between depression (depressive phase) and mania (maniac phase). Vestibular tests have been shown high sensibility and specificity as a biological marker for major depression. This exploratory investigation will measure and compare the vestibular activity of bipolar disorder patients during different phases ( 6 depressed phase, 6 maniac phase, 6 euthimic and 6 control healthy subjects).

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07
• Study First Submitted: 2016-07-06
• Study First Submitted QC: 2016-07-07
• Study First Posted: 2016-07-11
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-06
• Last Update Posted: 2024-05-07
• Primary Completion: 2024-07
• Study Completion: 2024-10

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Bipolar disorder I or II
• depressive phase of bipolar disorder
• maniac phase of bipolar disorder
• euthimic phase of bipolar disorder

Exclusion Criteria

• drugs addiction
• alcohol addiction
• neurologic condition, disorder

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Maniac phase	Vestibular test	Vestibular test
Depressive phase	Vestibular test	Vestibular test
Healthy subject	Vestibular test	Vestibular test
Euthimic phase	Vestibular test	Vestibular test

Primary Outcome Measures

Name	Time	Method
Vestibular test	December 2017