Evaluation of Effect of Internal Septum of Walnut on Blood Lipids

Not Applicable

Recruiting

• Conditions: Dyslipidemia.; Hyperlipidemia, Unspecified; E78.5

• Registration Number: IRCT20201227049850N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 January 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Obtain informed consent from patients.
Patients aged 25 to 70 years.
Patients with dyslipidemia who have serum LDL-C more than goal based on European Heart Association 2019 guideline despite receiving the maximum or maximum tolerable dose of statins. The therapeutic goals of LDL-C blood levels varies between 55 and 100 mg/dl based on other conditions and diseases in the study participants.

Exclusion Criteria

History of walnut allergy
Taking other herbal medicines
Immune system defects
Pregnancy
Renal failure (eGFR <30 mL / min / 1.73m2)
Liver failure (AST or ALT> × 3 ULN)
Uncontrolled thyroid disease (TSH 1.5 × ULN)
TG>350 mg/dl
Concomitant use of any medication containing estrogen or progesterone, systemic glucocorticoids, cyclosporine, tacrolimus, everolimus, sirolimus, antipsychotic drugs, psychotropic substances or alcohol
Neurological or psychiatric disorders that affect the acceptance of medication and the correct implementation of the study protocol
Lactation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ow-density lipoprotein cholesterol (LDL-C). Timepoint: Zero and 12 weeks after intervention. Method of measurement: Serum level measurement.