Association of Coronary Artery Disease With Lewis and ABO Blood Group Phenotypes- A Case Control Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 210
- 试验地点
- 1
- 主要终点
- Prevalence of Lewis and ABO blood group phenotypes in cases and controls.
研究概览
简要总结
Primary objective- To study the association of Lewis antigen and A, B, O blood group phenotypes with coronary artery disease patients attending the tertiary care hospital in Kerala.
The secondary objective-To find the association of Lewis antigen and A, B, O blood group phenotypes with smoking, alcohol use, diabetes, hypertension and dyslipidemia.
A case-control study to compare the prevalence of Lewis(a-b-) blood group among confirmed cardiac cases with the prevalence of the same among the general population and thereby find out if individuals with Lewis(a-b-) are more at risk of developing coronary artery disease. This may provide an economical and simple method for identifying subjects at increased risk for coronary artery disease and subsequently lead to more focused preventive measures and eventually to a specific treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 30 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients in the age group of 30-55 years at the time of data collection diagnosed with coronary artery disease based on positive changes in coronary angiogram (more than 70% coronary stenosis)
排除标准
- •Patients with other systemic illnesses like malignancy, autoimmune diseases.
- •Patients who were not willing to participate in the study.
结局指标
主要结局
Prevalence of Lewis and ABO blood group phenotypes in cases and controls.
时间窗: Lewis and ABO phenotype of the study participants was determined immediately after sample collection
Prevalence Lewis and ABO phenotype in cases will be compared to prevalence of the same in controls.
次要结局
未报告次要终点
研究者
Sree Raj V
Principal Investigator
Jubilee Mission Medical College and Research Institute