Evaluating Intracanal Medicaments: Nitrofurantoin, Nano-Silver Nitrofurantoin, and Ultracal in Postoperative Pain and Periapical Lesion Management - A Randomized Trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Reduction of post operative pain and resolution of periapical abscess
研究概览
简要总结
Background: After any initiated root canal procedure, chances of pain are present which may last for 2-5 days post the treatment.
Also, after effective appropriate root canal procedure, the periapical lesion should resolve over a period of time
Purpose: This randomized clinical trial aims to assess the effectiveness of nitrofurantoin and nitrofurantoin impregnated silver nanoparticles in the reduction of post operative pain and also in resolution of periapical lesion. By comparing outcomes with conventional method, we aim to identify the optimal approach for improving patient comfort and treatment success rate in endodontic practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- Male
入选标准
- •Patients between the age group of 18 – 60 years.
- •Physically and mentally healthy patients.
- •Maxillary and mandibular single-rooted teeth.
- •Clinically negative response or no tenderness on percussion.
- •No response on cold and EPT pulp sensitivity testing.
- •Patients Diagnosed with symptomatic apical periodontitis.
- •Radiographically presence of periapical radiolucency of 2-5 mm size.
- •Patients who were ready to participate in the study.
排除标准
- •Systemically compromised patients.
- •Multirooted tooth.
- •Weeping canal Positive history of antibiotics and analgesics use within the week before treatment.
- •Large periapical lesion Retreatment cases Patients taking antibiotics or immunosuppressive drugs six months before the study.
- •Pregnancy or lactation.
结局指标
主要结局
Reduction of post operative pain and resolution of periapical abscess
时间窗: 1 year
次要结局
- Time required for the resolution of the lesion to interpret the effectiveness of the treatment(1 year)
研究者
Dr Kalp R Kubadiya
Government Dental College and Hospital Jamnagar