Comparing occurrence of dry eye following cataract surgery by phacoemulsification and MSICS

Not Applicable

• Conditions: Health Condition 1: H259- Unspecified age-related cataract

• Registration Number: CTRI/2021/08/035502
• Lead Sponsor: JIPMER

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients with senile cataract above the age of 40 years undergoing cataract surgery by MSICS or phacoemulsification

Exclusion Criteria

1.Patients developing intra-operative or post- operative complications.

2.Glaucoma patients undergoing cataract surgery on prior topical anti-glaucoma medications.

3.Patients using any topical medications on a long-term basis for other ocular conditions like glaucoma, uveitis, etc.

4.Patients with lid abnormalities (entropion, ectropion, trichiasis) or exposure changes due to thyroid eye disease or facial nerve palsy.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Among patients undergoing cataract surgery by manual small incision cataract surgery and phacoemulsification: <br/ ><br> <br/ ><br>i.To compare ocular symptom scores, Schirmerâ??s I values, TBUT values and corneal surface staining score pre-operatively and post-op day 1, 3 weeks and 2 months <br/ ><br>ii.To compare tear film inflammatory markers (IL-1β, IL-6) and meibomian gland changes pre-operatively and post-op day 1, 3 weeks and 2 months <br/ ><br>iii. To compare impression cytology score pre-op, 3 weeks and 2 months.Timepoint: pre-operatively and post-op day 1, 3 weeks and 2 months

Secondary Outcome Measures

Name	Time	Method
To study the effect of age, gender and occupation on Schirmerâ??s I values, TBUT values, corneal surface staining score, impression cytology score, tear film inflammatory markers (IL-1β, IL-6) and meibomian gland changes in these patientsTimepoint: pre-operatively and post-op day 1, 3 weeks and 2 months