Investigation of Breathing Performance of Healthy Young Adult
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Peak cough flow
研究概览
简要总结
The study will recruit subject of healthy adult, COPD-like patient and patient with COPD to investigate the difference of respiratory performance. We will measure the body composition, respiratory muscle force, pulmonary function and performance of voluntary cough. The muscle thickness of abdominal muscle and diaphragm, assessment of diaphragm during different breathing pattern and the muscle activation during voluntary cough will also being determined. We hypothesized that there will be a significantly different between three group on the performance of voluntary cough, and the correlation between each variable will be further investigated.
详细描述
The specific aims of the study are:
- difference of respiratory muscle performance between three groups
- the correlation between respiratory symptom and pulmonary functional test
- difference of functional respiratory performance (peak cough flow of voluntary cough) between three groups
- muscle activation of abdominal muscle and diaphragm during performing voluntary force
- performance of diaphragm under different breathing load
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged 20 years or above
- •currently not being diagnosis as COPD
- •less than 4 times/week of aerobic exercise
- •COPD-like subject
- •Inclusion Criteria:
- •aged 20 years or above
- •currently not being diagnosis as COPD
- •presented of COPD symptoms (coughing, sputum production and dyspnea), last for 3 months and more than 2 years
- •score more than 1 on modified Medical Research Council (mMRC) or COPD Assessment Test (CAT)
- •COPD subject
- •Inclusion Criteria:
- •aged 20 years or above
- •currently being diagnosis as COPD
- •haven't participated in any pulmonary rehabilitation program in the past three months
排除标准
- •Untreated comorbidities for COPD
- •Postural asymmetries (Scoliosis, length discrepancy of the lower limbs or other previous surgical history of spine)
- •Chronic nonspecific lumbopelvic pain
- •Gynecological or abdominal surgery in the previous year
- •Pregnancy or post-delivery in the previous 6 months
- •Neurological or inflammatory disorders
- •Any conditions that may interfere with the data collection
结局指标
主要结局
Peak cough flow
时间窗: baseline
Peak coughing velocity of voluntary cough in liter/second
次要结局
- Respiratory muscle force(baseline)
- Pulmonary function test(baseline)
- Muscle activation during voluntary force(baseline)
- Diaphragm assessment(baseline)
- Muscle thickness during voluntary force(baseline)
研究者
Ching-Hsia Hung
Professor
National Cheng Kung University