The effect of using HCG in combination with the GnRh agonist for improving IVF outcomes
- Conditions
- infertility.female infertility
- Registration Number
- IRCT2017091736235N1
- Lead Sponsor
- Avicenna Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 164
Infertility due to male factor, tubal factor or unexplained; IVF less than 2 times; age between 18 and 40; BMI between 18 and 30; normal PRL and TSH; FSH less than 10; The minimum sperm count, 10 million and the minimum 3% of the sperms should have normal morphology. Exclusion criteria: AFC more than 15; E2 more than 3000 at trigger day or AFC more than 20; sensitization to HCG or gonadotropins; FSH more than 10 at third day of cycles or AFC less than 5; AUB; documented uterine anomaly in hysterogram or HSG; endometriosis (grade 3 and 4); Diabetes or uncontrolled HTN, kidney or liver dysfunction; PCO; Cancer, tumor, or pituitary adenoma; Ovarian cysts; hydrosalpinx; intramural or submucosal myoma larger than 6cm
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical pregnancy. Timepoint: 28 days after transfer. Method of measurement: vaginal sonography.
- Secondary Outcome Measures
Name Time Method Chemical pregnancy rate. Timepoint: 14 days after transfer. Method of measurement: BHCG test.;Number of embryo formation. Timepoint: 3 days after pancture. Method of measurement: Number.;OHSS. Timepoint: Till 2 weeks after ET. Method of measurement: sonography and symptoms.;Abortion. Timepoint: 6th and 12th week of pregnancy. Method of measurement: sonography.;Number of oocyte (2PN). Timepoint: Puncture day. Method of measurement: Number.