Comparison of two methods of double- trigger(GNRHa+HCG) and HCG-trigger on final oocyte maturation in normal responder patients.

Phase 2

• Conditions: Infertility.; Complication associated with artificial fertilization, unspecified; N98.9

• Registration Number: IRCT20190409043207N3
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 130

Inclusion Criteria

normal responder women
Age less than 42 years
BMI <30 Kg / m2
Estradiol Trigger Doses between 500 and 3000 pg / ml

Exclusion Criteria

Severe male factor
Untreated thyroid disorders
Severe uterine anomaly
Existence of pco criteria
FSH> 10 days of the third menstrual cycle and AMH <1
BMI less than 18 and more than 35
Predicting the the chance of of ovarian hyper stimulation syndrom(OHSS)
Hyperprolactinemia
Endocrine Disorders
Congenital adrenal hyperplasia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of follicles. Timepoint: From the tenth day of the cycle. Method of measurement: sonography.;Number of recovered oocytes. Timepoint: Oocyte recovery day. Method of measurement: observation.;Number of canceled cycles. Timepoint: Oocyte recovery day. Method of measurement: observation.;Number of embryo. Timepoint: 2 days after Oocyte recovery. Method of measurement: observation.;Embryo grading. Timepoint: 3 days after Oocyte recovery. Method of measurement: observation.;Number of transfered embryo. Timepoint: embryo transfere day. Method of measurement: observation.

Secondary Outcome Measures

Name	Time	Method
Chemical pregnancy rate. Timepoint: 14 days after embryo transfer. Method of measurement: positive B-HCG.;Clinical pregnancy rate. Timepoint: 4 weeks after embryo transfer. Method of measurement: fetal heart rate in sonography.