CTIS2023-503700-81-00
Active, not recruiting
Phase 1
Palliation of Dyspnea and Cough using Morphine in patients with Fibrotic Interstitial Lung Disease - Morpheus
Aarhus University Hospital0 sites110 target enrollmentNovember 22, 2023
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Fibrotic Interstitial Lung Disease
- Sponsor
- Aarhus University Hospital
- Enrollment
- 110
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •fibrotic interstitial lung disease, GAP (Gneder\-Age\-Physiology) score 2\-3, Presence of fibroses on HRCT (tractionbronchiectasis, honeycombing, loss of volume \>10% assessed by the investigator, MRC (Medical Research Councils) dyspnea score \= 3, Informed written consent, Age \= 18 år, Authoritative
Exclusion Criteria
- •Regular treatment with morphine or morphine analogues, Allergy or intolerance to morphine or morphine analogues, Ongoing infection or exacerbation, Patients with so severe impaired respiration that any form of worsening would be too risky (assessed by the investigator), Treatment with benzodiazepines (not benzodiazepine receptor agonists)
Outcomes
Primary Outcomes
Not specified
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