Effects of Progressive Elastic Band Resistance Training
- Conditions
- Prader-Willi SyndromeResistance Training
- Interventions
- Device: PWS elastic band training group
- Registration Number
- NCT03565081
- Brief Summary
Abnormal body composition with increased body fat mass and decreased lean body mass has been found in adults with Prader-Willi syndrome (PWS), contributing to reduced physical capacity and impairment. The aim of this study was to investigate whether progressive elastic band resistance training can improve physical motor performance and regional body composition in adults with PWS.
- Detailed Description
Six participants were enrolled in this pilot study. Following 24 weeks of progressive elastic band resistance exercise training, significant reduction was observed in their body weight, BMI, and regional extremities fat mass and percentage. Regarding the functional performances, there were also significant improvements in their hand grip strength, 3 meter timed up and go, 30 seconds sit to stand, and 2-min step up tests, as early as the 8th week of training. Balance function achieved significant improvements after 16 weeks of training.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 6
- PWS individuals who can cooperate with motor performances
- arthritis, fracture, or severe musculoskeletal deformities that would interfere with exercise training or motor performance
- severe cognitive impairment or parents who cannot read nor write.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description PWS elastic band training group PWS elastic band training group Genetically confirmed diagnosis of PWS participants were recruited. The PWS participants needed to have sufficient command of the Mandarin language to understand the study information and motivated to conduct the training program.
- Primary Outcome Measures
Name Time Method Changes in the balance functional physical assessment Changes from Baseline functional motor performance tests at 8 weeks, 16 weeks and 24 weeks Berg Balance Scale (0-56 points; 0-20= high fall risk; 21-40= medium fall risk; 41-56= low fall risk)
Change in the BMI body composition Change from Baseline body composition components at 6 months Body weight (km) and height (m) will be combined to report as BMI (kg/m2)
Change in the lean body mass of body composition Change from Baseline body composition components at 6 months Lean body mass (kg)
Changes in the handgrip strength functional physical assessment Changes from Baseline functional motor performance tests at 8 weeks, 16 weeks and 24 weeks hand grip strength (pounds),
Changes in the 30 second chair stand functional physical assessment Changes from Baseline functional motor performance tests at 8 weeks, 16 weeks and 24 weeks 30-second chair stand test (times)
Change in the percentage of body fat of body composition Change from Baseline body composition components at 6 months Regional percentage body fat (%)
Changes in the two minute step up functional physical assessment Changes from Baseline functional motor performance tests at 8 weeks, 16 weeks and 24 weeks 2 minute step up test (times)
Changes in the timed up and go functional physical assessment Changes from Baseline functional motor performance tests at 8 weeks, 16 weeks and 24 weeks timed up-and-go test (seconds)
Change in the body fat mass of body composition Change from Baseline body composition components at 6 months Fat mass (kg)
- Secondary Outcome Measures
Name Time Method