Whole Body Vibration and External Load Exercise Training on Cardiovascular and Autonomic Function in Obese Individuals
- Conditions
- Obesity
- Interventions
- Other: Unloaded-Whole Body Vibration (WBVT)Other: Loaded-Whole Body Vibration (WBVT)
- Registration Number
- NCT02679898
- Lead Sponsor
- Florida State University
- Brief Summary
Obesity is directly related to arterial dysfunction and negatively associated to muscle strength. High-intensity resistance exercise is the favored modality to offset muscle weakness, yet, adverse effects on arterial function (pulse wave velocity, wave reflection, and aortic and brachial blood pressures) have been observed. Conventional unloaded-whole body vibration training (WBVT) has improved arterial function in overweight/obese women but appears to be low-intensity. Nevertheless, the effects of moderate-intensity (by adding external load) WBVT on arterial and muscle function are unknown. Therefore, the purpose of this study was to examine whether loaded-WBVT would induce greater benefits than unloaded-WBVT on arterial and muscle function in young overweight/obese women. Furthermore, we examined whether these changes were similar to healthy lean young women.
- Detailed Description
The purpose of this study was to determine the effects of 6 weeks of loaded-WBVT on arterial stiffness, peripheral and aortic blood pressures, wave reflection, endothelial function, and muscle strength in overweight/obese women.
The specific aims of the study were:
1. To examine whether 6 weeks of loaded-WBVT was more beneficial than unloaded-WBVT in decreasing cardiovascular risk factors by assessing arterial stiffness (aortic, leg, and systemic), aortic blood pressures and wave reflection, brachial blood pressures, autonomic function, endothelial function, and blood flow (leg and arm).
2. To determine the extent to which 6 weeks of loaded-WBVT improved body composition measured by changes in fat and lean mass utilizing dual-energy x-ray absorptiometry and waist circumference.
3. To evaluate the effect of 6 wees of loaded-WBVT on muscle strength by using the one-repetition maximum test (leg press and chest press exercises).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
- Female
- 18 to 25 years of age
- Sedentary (less than 120 min per wk)
- 15 lean (Body mass index of 18-25 kg/m²)
- 45 overweight/obese (Body mass index of 27-39.9 kg/m²)
- Younger than 18 or older than 25 years of age
- Body mass index lower than 18 or higher than 39.9
- Physically active or competitively active
- Smokers
- Pregnant
- Irregular menstrual cycle
- Use of dietary supplementations (e.g.,L-arginine,L-citrulline,antioxidants)
- Any contraindications to exercise and/or whole-body vibration exercise
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Unloaded-Whole Body Vibration (WBVT) Unloaded-Whole Body Vibration (WBVT) Lower-body exercise training on a vibration platform Loaded-Whole Body Vibration (WBVT) Loaded-Whole Body Vibration (WBVT) Externally loaded lower-body exercise training on a vibration platform
- Primary Outcome Measures
Name Time Method Arterial Stiffness 6 weeks Aortic, leg, and systemic pulse wave velocity acquired through non-invasive sensors.
Pressure Wave Reflection 6 weeks Augmentation index acquired through radial tonometry.
- Secondary Outcome Measures
Name Time Method Autonomic Function 6 weeks Heart rate variability through electrocardiogram.
Blood Pressures 6 weeks Non-invasive measures of brachial and aortic blood pressures.
Endothelial Function 6 weeks Non-invasive arm and leg blood flow using vascular ultrasound positioned on my skin at rest and during increased blood flow.
Body Composition 6 weeks Measuring fat mass and lean mass from dual-energy x-ray absorptiometry.
Muscle Strength 6 weeks Using one-repetition maximum (1-RM) test for the leg press and chest press exercises.
Trial Locations
- Locations (1)
FSU College of Human Sciences
🇺🇸Tallahassee, Florida, United States