Oral Vitamin_C Effect in Treatment of Cornea

Phase 3

Conditions: Effect of Ascorbate on Healing Cornea Epithelium after Trans_epithelial Photorefractive Keratectomy.

Registration Number: IRCT20220601055053N1

Lead Sponsor: Karaj University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 160

Inclusion Criteria

Patients Candidated for TPRK during the 2022, June
Patients' eye score must be stable for at least one year
Patients must be more than 18 and less than 50 years old
Because this surgery is completely elective,both this surgery and using vitamin_c must be based on the patient's decisions

Exclusion Criteria

The patients were not interested in participating the study despite the comprehensive and complete explanations.
The patient is dead or get another proved disease such as collagen vascular diseases,romatoid arthritis,glandular diseases (hypo/hyper thyroidism and hypo/hyper parathyroidism),diabetes mellitus,hypertension,marfan syndrome,herpes keratitis,infectious diseases(HIV,hepatitis),cataract or any other past noticable ophthalmic disease or surgery that destroy the results of study in a way that examination can not be compared and assessed.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Corneal Epithelial Healing Time. Timepoint: Before the surgery,1week, 2weeks, first, second, third months after surgery. Method of measurement: slit lamp.;Corneal Haze Formation. Timepoint: Before the surgery,1week, 2weeks, first, second, third months after surgery. Method of measurement: slit lamp.;Crneal Epithelial Healing Quality. Timepoint: Before the surgery,1week, 2weeks, first, second, third months after surgery. Method of measurement: slit lamp.;The Quantity of Patient's Pain after Surgery. Timepoint: Before the surgery,1week, 2weeks, first, second, third months after surgery. Method of measurement: The McGill Pain Questionnaire(MPQ).

Secondary Outcome Measures