Inflammatory and nutritional changes during critical illness

Not Applicable

Completed

• Conditions: Critical care; Not Applicable

• Registration Number: ISRCTN79066838
• Lead Sponsor: Imperial College London (UK)

Brief Summary

2019 feasibility study results in ICU patients in: https://www.ncbi.nlm.nih.gov/pubmed/31511044 (added 13/09/2019) 2019 results in ICU patients in: https://www.ncbi.nlm.nih.gov/pubmed/31725748 (added 15/11/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-07-30
• Study Completion: 2013-03-01
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Part 1:
Intensive Care Unit (ICU):
Patients mechanically ventilated for > 48h

High Dependency Unit (HDU):
1. Trauma patients > 18 years.
2. Patients should be entered into the trial within 72h of ICU admission.

Part 2:
1. Trauma patients (head and multiple trauma) admitted to Intensive Care expected to be ventilated for > 48h
2. Over 18 years of age
3. Patients should be entered into the trial within 72 hours of ICU admission
4. Male and female participants
5. Between 18 - 95 years

Exclusion Criteria

Part 1:
Patients expected to be ventilated for < 48h; Non-trauma HDU patients.

Part 2:
1. Medical ICU patients
2. Surgical (non-trauma) ICU patients
3. Patients enrolled in another interventional clinical trial
4. Patients where enteral feeding is contraindicated
5. Cardiac failure
6. End Stage Renal Failure
7. Chronic Obstructive Pulmonary Disease
8. Chronic liver disease (cirrhosis)

Study & Design

• Study Type: Interventional
• Study Design: Not specified