Validation of PINI Score in ICU

• Conditions: ICU Patients

• Registration Number: NCT02742571
• Lead Sponsor: University Hospital, Clermont-Ferrand

Brief Summary

Prospective, observational clinical monocentric study in ICU; Relationship between Pronostic Inflammatory and Nutritional Index (PINI) (and biomarkers related to PINI) and mortality, morbidity and nutrition in ICU

Detailed Description

Main objective: to evaluate the relationship between PINI score and biomarker related to PINI, and 28 days mortality in ICU

Secondary objectives:

* to evaluate the relationship between PINI score (and biomarkers related to PINI) and morbidity in ICU : SOFA score, duration of ventilation, duration of antibiotherapy, duration of extra renal epuration, length of stay

* to evaluate the relationship between PINI score (and biomarkers related to PINI) and nutrition in ICU (type of nutrition, calorie content)

Study Timeline

• Study First Submitted: 2016-03-03
• Study Start: 2016-04
• Study First Submitted QC: 2016-04-14
• Study First Posted: 2016-04-19
• Status Verified: 2016-06
• Primary Completion: 2016-06
• Last Update Submitted: 2016-06-24
• Last Update Posted: 2016-06-27
• Study Completion: 2016-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Both patient in ICU

Exclusion Criteria

• minor patient
• No possibility to calculate PINI score
• Pregnant woman

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PINI Score	at day 1
Biomarkers related to PINI	at day 1
Mortality at 28 days	after admission

Secondary Outcome Measures

Name	Time	Method
Length of stay	at day 1
Duration of ventilation	at day 1
Duration of antibiotherapy	at day 1
Duration of renal replacement therapy	at day 1
Type of nutrition (enteral/parenteral)	at day 1
Calorie content per day	at day 1

Trial Locations

Locations (1)

CHU Clermont-Ferrand; 🇫🇷 Clermont-Ferrand, France