NCT00092339已完成3 期
A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effects of Rofecoxib 50 mg and Valdecoxib 40 mg in Patients With Postoperative Dental Pain
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 125
- 主要终点
- Overall analgesic effect as measured by total pain relief over 12 hours.
研究概览
简要总结
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
详细描述
The duration of treatment is 1 day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Impaction of a molar tooth requiring removal
排除标准
- •Any known allergy to the study drugs
结局指标
主要结局
Overall analgesic effect as measured by total pain relief over 12 hours.
次要结局
- Time to onset of analgesic, peak analgesic and duration of analgesic effects.
- Percent of patients using and amount used of supplemental analgesia within 8, 12, and 24 hrs.
- Overall safety and tolerability.
- Overall analgesic effect over 8 hrs.
研究者
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