A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effects of Rofecoxib 50 mg and Valdecoxib 40 mg in Patients With Postoperative Dental Pain

Merck Sharp & Dohme LLC0 sites125 target enrollmentAugust 1, 2002

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Postoperative Pain
Sponsor: Merck Sharp & Dohme LLC
Enrollment: 125
Primary Endpoint: Overall analgesic effect as measured by total pain relief over 12 hours.
Status: Completed
Last Updated: 8 years ago

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

The duration of treatment is 1 day.

Registry

clinicaltrials.gov

Start Date

August 1, 2002

End Date

September 15, 2002

Last Updated

8 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Sponsor

Responsible Party

Sponsor

Overall analgesic effect as measured by total pain relief over 12 hours.

Time to onset of analgesic, peak analgesic and duration of analgesic effects.
Percent of patients using and amount used of supplemental analgesia within 8, 12, and 24 hrs.
Overall safety and tolerability.
Overall analgesic effect over 8 hrs.