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Clinical Trials/NCT00092300
NCT00092300
Completed
Phase 3

A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled, Single Dose Study of the Effect of Rofecoxib 50 mg and Valdecoxib 20 mg in Patients With Postoperative Dental Pain

Merck Sharp & Dohme LLC0 sites450 target enrollmentMay 2002
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ConditionsPostoperative Pain
DrugsMK0966, rofecoxibComparator: valdecoxib

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Merck Sharp & Dohme LLC
Enrollment
450
Primary Endpoint
Overall analgesic effect over 12 hours.
Status
Completed
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

Detailed Description

The duration of treatment is 1 day.

Registry
clinicaltrials.gov
Start Date
May 2002
End Date
September 2002
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Impaction of a molar tooth requiring removal

Exclusion Criteria

  • •Known allergies to the study drug

Outcomes

Primary Outcomes

Overall analgesic effect over 12 hours.

Secondary Outcomes

  • Safety and tolerability.
  • Overall analgesic effect over 8 hours.
  • Time to onset of analgesic, peak analgesic and duration of analgesic effects.
  • Overall analgesic, time to onset of analgesic, peak analgesic, and duration analgesic effects

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